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One study in Germany, found gentian root provided relief of GI symptoms in 205 patients

doi:10.1097/mpg.0b013e31802f6424 82Lichtenstein GR, Feagan BG, Cohen RD, et al

CINeMA assesses six domains: within-study bias (informed by the Cochrane RoB 2 tool) ( The outcomes of interest were metabolic parameters reflecting the efficacy of each intervention in improving metabolic profiles among women with polycystic ovary syndrome

There were juice cleanses, boot camps, and crash diets like Keto

Though it's not ideal, these drugs can remain safe and effective to use after spending a fair amount of time at room temperature

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