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Risk: Higher cagrilintide dose will likely increase GI side effects and discontinuation rates

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There is a Common side effects of GLP-1 drugs are those of a gastrointestinal nature, such as nausea, vomiting, diarrhea, and constipation

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Glutamatergic neurotransmission In glutamatergic neurons, glutamate is packaged into synaptic vesicles (SVs) by vesicular glutamate transporters (VGLUT13) [26]