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Why the mechanism dictates slow titration The area postrema is also the brains emetic trigger zone
The albumin-binding CJC-1295 (DAC) healthy-adult study used weight-based subcutaneous dosing, with roughly 30 to 60 mcg/kg reported as the doses that were safe and relatively well tolerated in ascending single and multiple-dose trials of the DAC form a completely different pharmacokinetic entity from no-DAC
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