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For instance, Citrus limon -derived EVs reduce inflammation in macrophages by suppressing NF-B activity [136, 137], while TDEVs modulate NF-B target genes to achieve anti-inflammatory outcomes [32, 138]

Recently, there has been a lot of attention on the individual cannabinoids found in the cannabis plant like cannabidiol (CBD, cannabinol (CBN), cannabigerol (CBG), and others

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Transmission electron microscopy (TEM) was measured on a JEOL JEM-2100 instrument

Loss of neuronal GSH has also been linked to microglial activation and complement-mediated neurodegeneration, further emphasizing the link between redox imbalance and immune dysregulation (Hashimoto et al., 2023)