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for some of the changes, it has been demonstrated that they increase the concentration of the so-called inactive B12, but not the active B12

LCAT is synthesized in the liver and so named because it transfers a fatty acid from the C-2 position of a lecithin (phosphatidylcholine, PC) to the C3-OH of cholesterol, generating a cholesteryl ester and a lysolecithin

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[8] Kannengiesser K, Maaser C, Heidemann J, et al