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So, so they basically came to me at the onset of COVID in 2020, March of 2020
Consider the differences between 5-Amino-1MQ vs
Most common adverse events at all doses: Nausea (3355%, dose-related) Vomiting (1335%) Decreased appetite (1528%) Constipation or diarrhea (1020%) Injection-site reaction (510%) Dose-related dysesthesia signal: The TRIUMPH-4 trial identified a dose-related dysesthesia (nerve-tingling, paresthesia) signal: This is the most-flagged trial-level safety signal for retatrutide and the reason community doses cluster at 2-4 mg/week well below where the dysesthesia signal becomes prominent
However, your blood work results will likely reflect semaglutide use indirectly: lower A1C, improved triglycerides, and potentially changed kidney or liver markers
As a result, it is important to counsel patients that SSRIs can take a few weeks to provide a therapeutic response and to monitor mood and symptoms while taking SSRIs (10,11)
Laboratory profile of Semaglutide [PMID: 34305810] Laboratory literature summary: laboratory profile of Semaglutide
