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Their effect is dependent on glucose levels

J Vet Sci 2021;15:118-122

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This is exactly why we include vitamin C in our detox drips

Also, be aware with shots (many doctors still give cyanocobalamin shots) that though you may need higher doses of active B12s (like myself), you may not do well when given higher doses of cyanocobalamin in a shot because your body may not be able to do the conversions and you could have negative side effects