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Epub 2017 Dec 15

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However, there is also evidence pointing toward a hepatic origin of circulating DPP-4, and it has been suggested that the inclusion of some patients with unidentified liver disease may have contributed to the conflicting data regarding the association of plasma DPP-4 activity and T2DM

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Agonist was added at time 2 min and GTP (30 M) was added after the 12.1 minute timepoint