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Inadequate Se levels can increase the production of pro-inflammatory cytokines and enhance the autoimmunity process, leading to the development or exacerbation of conditions such as Hashimotos thyroiditis and Graves disease [48]

doi: 10.1096/fj.15-275404 24 VeskoukisASTsatsakisAMKouretasD

Further, the team found that cysteine restriction activates both the integrated stress response (ISR), a signaling network that restores cellular balance after stress, and the oxidative stress response (OSR), which is triggered by higher levels of reactive oxygen species (ROS) following depletion of glutathione, the bodys primary antioxidant

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While free radicals themselves arent necessarily bad, the problem happens when your body produces more free radicals than your body has antioxidants to neutralize