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When thiamine deficiency manifests with CNS involvement it is called Korsakoff encephalopathy (or Korsakoff psychosis) and is also commonly referred to as Wernicke-Korsakoff syndrome (WKS)

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NAC (Sigma-Aldrich, A7250) was diluted in drinking water at a concentration of 30 mM, the pH was adjusted to 7.00 and it was provided to mice ad libitum