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Correia AS, Grtner F, Vale N

Luciferase assay showed that the in vitro plasmid DNA delivery efficiency of pDNA/PamChol Cur delivered to lung epithelial cells was significantly higher than that of the pDNA group and exerted anti-inflammatory effects by inhibiting the nuclear translocation of NF-B ( in vitro and in vivo results demonstrated that PamHRchol/GA micelles decreased the inflammatory factor TNF- expression, with obvious anti-inflammatory effects

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45,74 In summary, expanding practical guidance for the management of GI adverse effects is critical to ensuring treatment continuity and maximizing clinical benefit

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