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Overexpression of NDI1 in HCT116 was achieved by transfecting 1 10 6 cells with plasmid PXMS-NDI1 DNA (PMXS-NDI1 was a gift from D

Vitamin C deficiency can also cause hair to grow in bent or coiled shapes due to defects that develop in the protein structure of hair as it grows ( Corkscrew-shaped hair is one of the hallmark signs of vitamin C deficiency but may not be obvious, as these damaged hairs are more likely to break off or fall out ( Hair abnormalities often resolve within one month of treatment with adequate amounts of vitamin C ( Summary Abnormally bent, coiled or corkscrew-shaped body hairs are a hallmark sign of vitamin C deficiency, but they may be difficult to detect, as these hairs are more likely to fall out

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This approach also enables exploration of broader biological phenomena such as angiogenesis, immune regulation, redox balance, and gene expression patterns associated with both acute injury responses and chronic inflammatory microenvironments (9-11)