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GLP-1 treatment suppressed the level of TNF- in an Alzheimers disease animal model brain induced by injection of STZ (Solmaz et al., 2015)

16 A challenge of comparing data between CVOTs is the inconsistency in the protocols for accurately detecting retinal changes

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Green JB, Bethel MA, Armstrong PW et al (2015) Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes

Increasing Dose: What the Evidence Shows A common misconception is that tolerance means the drug no longer works