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Teams must continuously gather PBM-specific access data (denial rates, turnaround, fill rates) to identify bottlenecks
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Important safety considerations include contraindications in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, caution in those with a history of pancreatitis, increased risk of gallbladder disease, potential for acute kidney injury with dehydration, and possible worsening of diabetic retinopathy with rapid glycemic improvement
Protein intake of 20 grams in the shake causes no issues for most people
Knoepfler's 2023 commentary on BPC-157 made a narrower point