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On the other hand, Kupffer cell-derived IL-10 can restrict the injury by limiting iNOS induction [100, 101] and at later time points by promoting pro-regenerative gene expression in hepatocytes surrounding the area of necrosis [102]

The convergence of Type-2 diabetes and obesity care is no longer clinical alone - its a strategic commercial battleground

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doi: 10.1088/1748-6041/9/2/025002 303 ZambelliV

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Even on the current addressable market for obesity only, we see scope for better-than-expected growth in the US alone, as the penetration rate in US adults is still small at 1.5%