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Both weight loss medications work by mimicking natural hormones that regulate appetite and insulin levels
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But here's what matters: your body already produces GLP-1 naturally, and specific foods and nutrients can genuinely influence how much you make
Which HRT delivery methods are affected Affected by GLP-1 medications (oral delivery): Oral estrogen tablets (conjugated equine estrogens, estradiol) Oral progesterone (micronized progesterone, such as Utrogestan) Oral progestins (norethisterone, medroxyprogesterone) Oral testosterone (testosterone undecanoate) NOT affected by GLP-1 medications (non-oral delivery): Transdermal estrogen patches Topical estrogen gels and creams Vaginal estrogen rings or suppositories Progesterone-releasing IUD (Mirena) Transvaginal progesterone Testosterone injections Testosterone pellets Testosterone patches or gels The distinction is simple
Cost & Insurance Coverage Comparison Sermorelin is more affordable and often used long-term, whereas semaglutide without insurance can be expensive
