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Menstrual cycle changes have been reported by some women, likely related to hormonal shifts that accompany weight changes and metabolic alterations
Promotes joint, bone & connective tissue health
Tirzepatide does not prevent this metabolic adaptation entirely, but the degree of slowdown may be less than with diet-only weight loss
More on body composition changes here
Pharmacol Res - Mod Chinese Med [Internet]
Studies have shown that, pharmacological blockade or decreased expression and function of CB1R can disrupt the negative feedback of the HPA axis, leading to increased circulating CORT levels (151)
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