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Slowing dose escalation is the standard approach, since gastrointestinal effects usually ease as the body adjusts over several weeks

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However, the overall filling of the open wound to skin level with granulation tissue was significantly slower in the control group by 19 days compared to both the TCC group by 10 days and the zinc oxide group by 12 days, highlighting the positive impact of both active treatments on tissue regeneration [2]

Changchun Xiao (Sanofi China) for the Rosa26 -CTV vector

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