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Metabolic syndrome and smoking are independent risk factors of male idiopathic infertility

Ranganathan, J.V

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While directly measuring neuroprotection in living patients is technically unfeasible, alternative strategies, such as monitoring pro-inflammatory markers or neuroprotective cytokines in the plasma of patients receiving istradefylline, could offer valuable mechanistic insights and serve as surrogate indicators of therapeutic activity [485]

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Menafra D, de Angelis C, Garifalos F, Mazzella M, Galdiero G, Piscopo M, Castoro M, Verde N, Pivonello C, Simeoli C, Auriemma RS, Colao A, Pivonello R