and actually SARS-CoV-2 causing COVID-19, all are characterized by persistent inflammation, continuous production of reactive oxygen/nitrogen species and oxidative stress that predominate over the antioxidant defenses (GSH and free radical scavenger enzymes) resulting in cell/tissue/organ aging associated with early (premature) chronic inflammation/inflammaging. We propose that, although inflammaging was introduced for the aging process (276289), it could also apply to early (premature) tissue and organ aging associated with cell and tissue damage caused by excessive oxidative stress and lack of adequate antioxidant defenses, especially low GSH levels, in younger individuals
Sensitive skin may do better with slower introduction or lower-strength products
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Epithalamin is a related pineal peptide preparation containing Epithalon, that has been purported to potentially increase the average lifespan of various experimental models by 1131% and may reduce mortality in murine models by a suggested 52%
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