The standard titration schedule starts at 2.5 mg per week for 4 weeks, then increases to 5 mg per week for another 4 weeks, with subsequent increases of 2.5 mg every 4 weeks up to a maximum of 15 mg per week (Mounjaro prescribing information, Eli Lilly)
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Physiological Sciences, Federal University of Santa Catarina, Florianpolis, Brazil
Building in regular assessment points prevents plateaus and catches problems early
If your BMI is above 35 and your clinical goal is substantial weight reduction, a microdose may not move the needle enough to improve metabolic markers like HbA1c, blood pressure, or triglycerides
Wegovy and Ozempic (semaglutide) from Novo Nordisk are approved for chronic weight management and type 2 diabetes, respectively