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55 used a classical NKG2D CAR-T in different models of senescence to illustrate the specificity of this approach as senolytic approach

Recall that we abbreviate molar concentration with square brackets: $[A^+]$ means "the molar concentration of $A^+$." We now "invent" the solubility product expression as the product of the molar concentration of the dissociated ions: $$A_mB_n \rightleftharpoons mA^+ + nB^-$$ It turns out that this product will be constant for a given ionic compound once equilibrium is established between the solid and the ions

It appears to normalize the inflammatory response, allowing necessary acute inflammation while preventing the chronic state that impairs healing

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PMID: 25187433

Presented for research literature review only Simi T et al