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Keep an eye out for serious symptoms

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When muscle drops too much during weight loss, patients may experience: Reduced strength Lower energy Poorer exercise tolerance Increased frailty risk Greater chance of weight regain Less favorable body shape after weight loss Reduced metabolic flexibility Higher risk of functional decline with aging This is one reason the term skinny fat has become common in wellness conversations

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Phase 3 trials evaluating oral semaglutide in early-stage symptomatic Alzheimers disease did not meet their primary endpoints, tempering the earlier hypothesis that GLP-1s might offer direct neuroprotective benefits

These are both involved in DNA repair and longevity