1084: 23549 Vinik AI, Liuzze FJ, Holland MT, et al
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This pulsatile pattern is central to GH biology and is shaped by GHRH, somatostatin, ghrelin, sleep, age, and metabolic state. One important finding from CJC-1295 with DAC research is that GH secretion remained pulsatile even during prolonged GHRH analog stimulation. This helps distinguish GHRH analogs from direct GH replacement, which bypasses upstream pituitary signaling
Drugs 29 , 12951308 (2020)
This allows MCFAs to be effectively converted into energy for its immediate utilization rather than being involved in cholesterol biosynthesis and fat accumulation (Duttaroy 2021)