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Similarly, isoniazid, a frontline antitubercular agent, is implicated in neuropathies due to pyridoxine depletion and resultant GABAergic dysfunction, contributing to seizure disorders and metabolic encephalopathy [34]

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CrossRef PLEIOTROPIC EFFECTS OF GLP-1 RECEPTOR AGONISTS: A LITERATURE REVIEW Wiktoria Marzec, Hanna Maruchniak, Paulina Biedro, Anna Skrzypek, Maciej Hutkowski, Mikoaj Zbroek, Zuzanna Chwostek, Bartomiej Kosiarski, Patrycja Markowicz, Krzysztof Biyk International Journal of Innovative Technologies in Social Science.2026;[Epub] CrossRef Potential Antiarrhythmic Mechanisms of Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs) Jianhong Li, Kun Fu, Jiaqian Zhao, Ying Zou, Li Li, Qiuyuan Huang, Limei Long, Xianhong Ou, Ming Lei, Chunxiang Zhang, Xiaoqiu Tan, Tangting Chen Drug Design, Development and Therapy.2026

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By the time a clinical diagnosis is established, 60%80% of dopaminergic neurons in the substantia nigra pars compacta (SNc) have already been lost, rendering neuroprotective interventions largely ineffective [7, 8]

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Petersburg Institute of Bioregulation and Gerontology under Professor Vladimir Khavinson

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