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If we find it, thats going to be really interesting, both to understand mechanisms
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PMID: [12897423] REFERENCES National Center for Biotechnology Information
Sinus tachycardia: A regular increase in heart rate that originates from the sinus node, the hearts natural pacemaker
Diarrhea can also occur, sometimes alternating with constipation
These include (i) rational drug combinations targeting parallel or converging signaling cascades, (ii) the use of allosteric inhibitors or degraders that disrupt key signaling hubs, (iii) vertical inhibition along a single pathway to prevent upstream feedback reactivation, and (iv) the application of systems biology and network modeling to predict synthetic lethal vulnerabilities
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