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Science (New York, N.Y.)

Compared to the wtVLP, our sVLP, which is derived from the PV1-SC7 mutant, carries seven amino acid substitutions: VP1 V196L, VP1 H248P, VP2 T25A, VP2 D57E, VP3 Q178L, VP3 L119M, and VP4 R18G (Fig

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The Phase 2 trial enrolled 338 adults for 48 weeks

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