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Forest plot of Semaglutide versus comparators on the risk of overall Respiratory diseases
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The FDA shortage designation for both GLP-1s was resolved in early 2025 tirzepatide in December 2024, semaglutide on February 21, 2025 and by May 22, 2025, large scale compounding was legally prohibited
The USFDA and EMA are placing more control on the consistency in the batches, GMP records and cold-chain documentation
According to MHRA-approved prescribing information, patients typically begin with 0.25 mg once weekly for four weeks to allow the body to adjust to the medication and minimise gastrointestinal side effects such as nausea and vomiting
To better understand how the emerging evidence is shaping actuarial thinking, we interviewed a panel of health and life actuaries about prescribing trends, coverage decisions, and signals they are watching across markets
