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While the classical incretin concept is based on the assumption that incretin hormones such as GIP and GLP-1 reach their main endocrine target cells via the bloodstream, there is some evidence that GIP (and possibly GLP-1) can be produced in relatively small amounts in endocrine alpha-cells of the pancreas [3]
What should I do if I experience dizziness or weakness
The effect is dose-dependent: higher doses are more likely to trigger symptoms, which is why slow dose escalation is the standard medical approach
Taken in the context of previous investigations, this study suggests that GGT interpretation should best be flexible based on the patient population under consideration
Foods to consider reducing or avoiding during symptomatic periods: High-sulphur foods: eggs, red meat, poultry skin, garlic, onions, leeks, and cruciferous vegetables High-fat or fried foods, which may further delay gastric emptying Highly processed foods and those containing artificial sweeteners, which may worsen loose stools in some people Caffeine and alcohol, both of which can irritate the gastrointestinal tract Foods that may be better tolerated: Plain, low-fat carbohydrates such as rice, plain pasta, and toast Cooked vegetables rather than raw, which are generally easier to digest Lean proteins such as fish or tofu Probiotic-containing foods such as live yoghurt, which some people find helpful for gut comfort