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Patients mean age was 61.6, with 53.2% being women and 46.8% men

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The study found that the iron concentration in the vitreous of human OT patients decreased significantly, suggesting that ferroptosis is involved in the pathogenesis of OT ( 2.9 Other ocular defects in zebrafish In zebrafish embryos, excessive selenium disrupted mitochondrial morphology and elevated ROS-induced oxidative stress, apoptosis and ferroptosis ( 3 Pharmacological agents targeting ferroptosis in retinal diseases The critical role of retinal cell ferroptosis in various retinal diseases suggests a potential therapeutic role of ferroptosis inhibitors in related diseases