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10.1016/j.jhazmat.2013.12.018 23 BoominathanR.DoranP
Most foods naturally contain dietary glycation products, and dAGEs in particular, often in amounts that can exceed their endogenous generation, making the daily diet a major source of glycotoxins ( Figure 3 To date, approximately forty distinct AGEs have been identified in various materialsfrom foods to human fluids and tissues (52)
236 Furthermore, glucose starvation leads to a suppressed lactate/pyruvate cycle, which inhibits neovascularization, hypoxia-induced vascular epidermal growth factor activation, and angiogenesis, and causes ultimate necrosis in tumor cells, especially for colon adenocarcinoma xenografts
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Cng dng chng oxy ha cc mnh ca Glutathione mang li rt nhiu li ch tuyt vi cho ln da nh: gim nm sm da, lm trng da, ngn nga cc du hiu lo ha
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