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3458-A METABOLIC BIOMARKER CONSTELLATIONS ALLOW SIMULTANEOUS AND INTEGRATED LIVER AND KIDNEY FUNCTION MONITORING IN CHRONIC LIVER DISEASE Frank Stmmler 1 , Laurence Derain-Dubourg 2 , Sandrine Lemoine 2 , Jeffrey Meeusen 3 , Surendra Dasari 3 , John Lieske 3 , Andrew Robertson 1 and Eric Schiffer 1 , (1)Numares AG, (2)Hospices Civils De Lyon, (3)Mayo Clinic Background: Renal impairment often occurs in liver disease

Pharmacology & Therapeutics, 117(1), 105122

These could consist of sensations like nausea, abdominal pain, stomach pain, and headache, among other symptoms

How soon can I start after my consult

Contact your clinician sooner if sleep problems are causing clear daytime impairment, if palpitations, reflux, or nighttime glucose changes repeatedly wake you, or if the pattern starts to resemble clinical insomnia instead of a short adjustment period

Results showed non-inferiority (Rybelsus did not increase cardiovascular risk vs placebo) but no significant reduction in MACE (Husain et al., Circulation, 2019)