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Aydin , Meijnikman AS, de Jonge PA, et al
1 maggio 2024 [citato 5 giugno 2024];46(3):1935
CYP3A4 change | Unpredictable trough levels | Major | Measure drug levels q1 to 2 wk during dose escalation | | Levothyroxine | Gastric emptying delay | Reduced Cmax ~30% | Moderate | Administer 60 min before any other oral drug
Participants were randomized to receive retatrutide at doses of 1, 4, 8, or 12 mg weekly, or placebo, for 48 weeks
Given current market dynamics, a low-cost product may not be widely available in the near term
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