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Some studies show constipation rates reaching 25-35% in people with obesity who take these medications [2]
This regulation is bidirectional: the peptide can increase or decrease NO production depending on the pathological context, thereby contributing to vascular protection and inflammation reduction
GLP-1 medications may cause diarrhea (or frequent loose stools)
This can reflect either vasogenic or cytotoxic edema, with the latter indicated by a reduction in the ADC (apparent diffusion coefficient)
Aquac Nutr 27:25752586
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