Published binding studies have demonstrated 10-100 fold increased potency compared to native alpha-MSH at the MC1R
It is vegan-friendly and highly absorbable, free from hormones, sulfates, and common allergens, and contains no heavy metals, mineral oil, or carcinogenic sunscreen ingredients
Mean percent body weight change at 80 weeks, by dose: Retatrutide 4 mg : 19.0% (47.2 lbs) Retatrutide 9 mg : 25.9% (64.4 lbs) Retatrutide 12 mg : 28.3% (70.3 lbs) Placebo : 2.2% (5.5 lbs) Responder rates at the 12 mg dose are the more interesting number for clinicians
Patients should be counseled that these medications are not recommended during pregnancy or lactation
10.1016/S0140-6736(21)02188-7 7 DubskyM.VelebaJ.SojakovaD.MarhefkovaN.FejfarovaV.JudeE
In fact, many doctors have been prescribing Ozempic for off-label use to treat obesity