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Pharmacol Res (2021) 163:105283
doi: 10.1093/ajcn/77.2.326 359 ChuCJiangJYuLLiYZhangSZhouWet al
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Briefly, on day 0, iPSCs were dissociated with TrypLE Select (GIBCO, Thermo Fisher Scientific, MA, USA) and disseminated on a mixed coating of poly-l-lysine (final 0.0002% v/w, Merck, Darmstadt, Germany), and Matrigel (final 2% v/v, Corning, NY, USA)
In fibroblast and tendon cell culture models, treatment with BPC-157 has been associated with increased phosphorylation of focal adhesion kinase (FAK) and downstream activation of Rac1/Cdc42 GTPases, facilitating actin cytoskeleton remodeling relevant to cell motility and extracellular matrix remodeling studies
