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FDA for clinical trials in patients with relapsed or refractory multiple myeloma (R/R MM)
The researchers found a similar effect in humans, though they say more study is needed
dose-dependent tolerability
These features are designed to enhance peptide stability and extend activity during laboratory experiments
"The burden is on us as physicians to be able to modulate the dose."
Three structural features a lid domain, a glycine-rich loop, and an alanine-rich loop define the active site of hGS (Figure 4B)
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