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The fact that covering GLP-1s under Medicare Part D for authorized uses is already making a mark on total Part D program spending could be a sign of even higher spending to come as Part D plans are now able to cover Wegovy for its heart health benefits, as other uses for GLP-1s are approved, and as policymakers consider legislation that would authorize Medicare to cover obesity drugs

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These small changes are the earliest visible signs of the transformation that will accelerate dramatically over the coming months

Using semaglutide and orlistat together may lead to additional benefits for overall metabolic health: Better Blood Sugar Control: Semaglutide helps stabilize blood sugar levels by reducing the amount of glucose released into the bloodstream

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See our separate article on the bupropion-GLP-1 combination