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Smaller doses also lessen the cost of the drug, and may help avoid side effects
It is well-known that the gut metabolite sodium butyrate (NaB) could promote GLP-1 secretion from intestinal L cells
Understanding GLP-1 Medications GLP-1 stands for Glucagon-Like Peptide-1, a naturally occurring hormone in the body
GLP-1 RAs showed trends toward improvements in endocrine and metabolic, cardiovascular, renal, and respiratory outcomes, cognitive function, with a potential reduction in fracture risk and all-cause mortality in certain populations
Those participants also tended to walk faster after treatment, suggesting better physical function
It is reasonable to take both observations seriously as hypotheses, with two cautions: Phase 2 trials are smaller, and the trial populations are not identical to GLP-1 trial populations
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