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New insights into the mechanisms of diabetic neuropathy
2014 Dec;50(3):1059-84
Molecular Neurobiology, 34 , 163179
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Their recommendations focus on treatment at validated doses that were studied in large clinical trials
A prescriber may hold the dose because side effects have not settled, because you are still losing steadily, because the plateau is only two or three weeks old and that is normal variation rather than a signal, because something other than the dose explains it liquid calories, a new medicine, poor sleep, missed doses or because a symptom needs investigating first
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