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Common side effects of phentermine include increased heart rate, elevated blood pressure, insomnia, dry mouth, nervousness, and constipation

Even if GLP-1 monotherapy is found to be less effective for opioid cessation than a combination therapy, it has the potential to reach vastly more patients and reach them at earlier stages, including the high percentage of patients who have refused existing medication options

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Do not read too much into week one results

S.GuX.et al (2019)

Studies consistently show that dietary compliance decreases over time regardless of the specific diet