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Mol Aspects Med 30:4259
Jing Z, Qilian Z, Haiquan W
Garbett K, Ebert PJ, Mitchell A, Lintas C, Manzi B, Mirnics K, et al
Oxidative stress occurs when there is an imbalance between free radicals (unstable molecules) and antioxidants in your system
Cytoplasmic protein aggregates, a pathological feature of ALS, disrupt key cellular degradation mechanisms, including both the ubiquitin-proteasome system and autophagy pathways, resulting in catastrophic failure of protein homeostasis
Clinical interest has focused on GLP-1 as GIP is no longer active in Type 2 diabetes
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