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They are not antidepressants

Furthermore, GLP-1 and glucose-dependent insulinotropic polypeptides have been shown to induce substance P release from sensory nerves expressing TRPV1 and TRPA1, broadening the potential pain modulation mechanisms of GLP-1 and suggesting their application in peripheral pain management 64

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There is mild to moderate swelling for the first few days, as well

One way it helps is by naturally boosting levels of GLP-1