They have also been shown to have beneficial effects on cardiovascular (CV) risk factors by improving obesity, hypertension, and the lipid profile ( Therapeutic Targets in Diabetic Kidney Disease DKD is a risk factor for both ESRD and CVD
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About SOUL SOUL was a multicenter, international, randomized, double-blind, parallel-group, placebo-controlled, phase 3b cardiovascular outcomes trial, with 9,650 participants enrolled
GLP-1 receptors are expressed on certain immune cells, including T-cells
Proc Natl Acad Sci (2009) 106:108538
Those side effects may persist during treatment