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Int J Obes (Lond) 38(6):784793 Hoffman S, Adeli K (2021) Glucagon-like peptide (GLP)-1 regulation of lipid and lipoprotein metabolism

The data on newer agents are even more striking, with tirzepatide demonstrating significantly greater weight loss (20.2%) than semaglutide (13.7%) in head-to-head trials

Weve been able to show that genetics is also playing a role, said Adam Auton, vice president of human genetics at 23andMe Research Institute and one of the authors of the study

Before tirzepatide, Lilly was developing its own GLP-1-only agonists (e.g., dulaglutide) and amylin analogs, and it launched baricitinib/therapies in inflammation

& Krueger, J