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Keep ambient-temperature handling time as short as practical to support compound integrity

The most common regimens include: 250/125 mg every 8 hours 500/125 mg every 8 hours 875/125 mg every 12 hours The exact dose depends on the infections severity and location

Non-uniform helical refinement with D1 symmetry (C2 symmetry perpendicular to the helical axis) imposed resulted in a 3.7 map with a refined helical twist of 108.4 and a rise of 51.2

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