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Most patients do not notice immediate effects

Furthermore, the main indications in the included cases were type 2 diabetes mellitus and obesity, which are potential risk factors for SSIBs

In Phase 2 clinical research, retatrutide demonstrated body weight reductions of up to 24.2% over 48 weeks, the largest reported for any incretin-based compound at that stage of development [8]

An additional priority of upcoming studies will be to define the key neurocircuits

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