The primary reason is that the medications influence many of the same biological systems
The full therapeutic effect requires sufficient drug concentration across all relevant tissues simultaneously, which is precisely what the dose escalation schedule is designed to achieve
It plays a vital role in neutralizing free radicals and oxidants, which cause cellular damage, aging, and various diseases
Losing weight especially losing it quickly changes the way your joints handle pressure, shifts inflammation levels, and can even lead to temporary imbalances in hydration and electrolytes
As mentioned, people lose 24-28.7% of their body weight on average
If you switch between drugs (for example, Wegovy to Zepbound), follow the gap rule for the drug you are starting next