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Mercer PF, Woodcock HV, Eley JD, Plate M, Sulikowski MG, Durrenberger PF, et al

Preclinical studies indicate that microbiota modulation via diet or probiotics can reduce neuroinflammation and amyloid burden, with some animal models showing improved cognitive outcomes

Native GIP produces full agonism of the human GIPR (half maximal effective concentration (EC 50 ) = 6.6 pM) and AMG 133 fully antagonizes native GIP (Extended Data Fig

However, restoring its expression level through genetic intervention effectively inhibits the proliferation of bladder cancer cells and promotes cuproptosis

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