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Inject slowly to reduce tissue trauma

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Some anecdotal evidence points to a potential connection between vitamin B12 shots and improved skin health or anti-aging effects

If a significant part of this mechanism relies on re-absorption from bile that would be an issue due to lack of intrinsic factor breaking the "enterohepatic recirculation"

extended use requires careful monitoring

One study found that lactating women taking 2-60 mg of niacin daily had milk niacin concentrations of 1.17-2.75 g/mL